R-(+)-Cotinine
Modify Date: 2025-09-11 00:16:18
R-(+)-Cotinine structure
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Common Name | R-(+)-Cotinine | ||
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| CAS Number | 32162-64-4 | Molecular Weight | 176.22 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H12N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of R-(+)-CotinineR-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs[1]. |
| Name | (-)-cotinine |
|---|---|
| Synonym | More Synonyms |
| Description | R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs[1]. |
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| Related Catalog | |
| In Vitro | R-(+)-Cotinine (1 μM) significantly enhances the Ach (40 μM)-evoked current in human α7 nAChRs[1]. |
| In Vivo | R-(+)-Cotinine (0.3-10 mg/kg; a single i.p.) enhances the effects of a subthreshold dose of Donepezil (0.5 mg/kg) on novel object recognition (NOR) performance[1]. |
| References |
| Molecular Formula | C10H12N2O |
|---|---|
| Molecular Weight | 176.22 |
| Exact Mass | 176.09500 |
| PSA | 33.20000 |
| LogP | 1.31280 |
| InChIKey | UIKROCXWUNQSPJ-SECBINFHSA-N |
| SMILES | CN1C(=O)CCC1c1cccnc1 |
| HS Code | 2933990090 |
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| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| COTININE (+)- |
| R-(+)-Cotinine |
| R-(+)-COTININE ((5R)-(+)-1-METHYL-5-(3-PYRIDIYL)-2-PYRROLIDINONE) |