ZINC00784494
Modify Date: 2025-08-26 19:41:10
ZINC00784494 structure
|
Common Name | ZINC00784494 | ||
|---|---|---|---|---|
| CAS Number | 317328-17-9 | Molecular Weight | 362.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H14N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZINC00784494ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1]. |
| Name | ZINC00784494 |
|---|
| Description | ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1]. |
|---|---|
| Related Catalog | |
| Target |
LCN2[1]. |
| In Vitro | ZINC00784494 (0.01-100 µM; 72 h) reduces cell proliferation and cell viability in SUM149 cells[1]. ZINC00784494 (1, 10 µM; 15 min, 1 h) reduces the p-Akt levels in SUM149 cells[1]. Cell Viability Assay[1] Cell Line: SUM149 cells Concentration: 0.01-100 µM Incubation Time: 72 h Result: Reduced cell viability at concentrations of 1 µM or lower. Western Blot Analysis[1] Cell Line: SUM149 cells Concentration: 1, 10 µM Incubation Time: 15 min, 1 h, 24 h Result: Reduced the p-Akt protein levels 15 min and 1 h and changes in the p-Akt protein levels were not observed at 24 h. |
| Molecular Formula | C20H14N2O3S |
|---|---|
| Molecular Weight | 362.40 |
| InChIKey | KUKVCIJGVUUCEV-UHFFFAOYSA-N |
| SMILES | CC(=O)c1cccc(Nc2nc(-c3cc4ccccc4oc3=O)cs2)c1 |