Tiamenidine

Modify Date: 2024-01-09 22:26:18

Tiamenidine Structure
Tiamenidine structure
Common Name Tiamenidine
CAS Number 31428-61-2 Molecular Weight 215.70
Density 1.52g/cm3 Boiling Point 305.1ºC at 760mmHg
Molecular Formula C8H10ClN3S Melting Point 152°
MSDS N/A Flash Point 138.3ºC

 Use of Tiamenidine


Tiamenidine (HOE 440) is an orally active α2-adrenergic receptor agonist with antihypertensive effect. Tiamenidine is used as an antihypertensive agent for hypertension research[1].

 Names

Name N-(2-chloro-4-methylthiophen-3-yl)-4,5-dihydro-1H-imidazol-2-amine
Synonym More Synonyms

 Tiamenidine Biological Activity

Description Tiamenidine (HOE 440) is an orally active α2-adrenergic receptor agonist with antihypertensive effect. Tiamenidine is used as an antihypertensive agent for hypertension research[1].
Related Catalog
Target

IC50: α2-Adrenergic Receptor[1]

References

[1]. D M Roden, et al. Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers. Clin Pharmacol Ther. 1988 Jun;43(6):648-54.  

 Chemical & Physical Properties

Density 1.52g/cm3
Boiling Point 305.1ºC at 760mmHg
Melting Point 152°
Molecular Formula C8H10ClN3S
Molecular Weight 215.70
Flash Point 138.3ºC
Exact Mass 215.02800
PSA 64.66000
LogP 1.91840
Index of Refraction 1.717

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Hoe-440
Tiamenidinum
Hoe-42-440
Tiamenidine
Tiamenidina
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Tiamenidine
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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