HUP30
Modify Date: 2025-09-12 14:55:13
HUP30 structure
|
Common Name | HUP30 | ||
|---|---|---|---|---|
| CAS Number | 312747-21-0 | Molecular Weight | 305.35200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H15N3O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of HUP30HUP30 is a vasodilating agent. HUP30 stimulates soluble guanylyl cyclase, activate K+ channels, and blocks extracellular Ca2+ influx[1]. |
| Name | N-(6-nitro-1,3-benzothiazol-2-yl)cyclohexanecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | HUP30 is a vasodilating agent. HUP30 stimulates soluble guanylyl cyclase, activate K+ channels, and blocks extracellular Ca2+ influx[1]. |
|---|---|
| Related Catalog | |
| In Vitro | HUP30 抑制苯肾上腺素诱导的主动脉收缩，IC50 值为 3.9 μM[1]。 HUP30 (100 μM) 增加去氧肾上腺素刺激的主动脉中的 cGMP 水平[1]。 HUP30 对 25/30 mM K+ 收缩的大鼠主动脉环产生解痉作用，IC50 值为 7.5 μM[1] . HUP30 (3-100 μM) 抑制苯肾上腺素诱导的细胞外 Ca2+ 内流和 Ca2+ 动员[1]。 HUP30 (10-100 μM) 抑制单尾动脉肌细胞中的电流[1]。 |
| References |
| Molecular Formula | C14H15N3O3S |
|---|---|
| Molecular Weight | 305.35200 |
| Exact Mass | 305.08300 |
| PSA | 119.54000 |
| LogP | 4.89600 |
| InChIKey | VMAKFFKOZSLHDW-UHFFFAOYSA-N |
| SMILES | O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)C1CCCCC1 |
![6-Nitrobenzo[d]thiazol-2-amine structure](https://image.chemsrc.com/caspic/389/6285-57-0.png)
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| f0327-0054 |