(R)-MLN-4760

Modify Date: 2025-08-27 04:15:47

(R)-MLN-4760 Structure
(R)-MLN-4760 structure
Common Name (R)-MLN-4760
CAS Number 305335-29-9 Molecular Weight 428.31
Density N/A Boiling Point N/A
Molecular Formula C19H23Cl2N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-MLN-4760


(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer[1].

 Names

Name (R)-MLN-4760

 (R)-MLN-4760 Biological Activity

Description (R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer[1].
Related Catalog
Target

IC50: 8.4 nM (ACE2)[1]

In Vitro (R)-MLN-4760 (compound 16RS) is the less active isomer of MLN-4760[1].
References

[1]. Dales NA, et, al. Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors. J Am Chem Soc. 2002 Oct 9;124(40):11852-3.

 Chemical & Physical Properties

Molecular Formula C19H23Cl2N3O4
Molecular Weight 428.31
InChIKey NTCCRGGIJNDEAB-SJORKVTESA-N
SMILES CC(C)CC(NC(Cc1cncn1Cc1cc(Cl)cc(Cl)c1)C(=O)O)C(=O)O
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