1-(4-Trifluoromethylphenyl)piperazine

Modify Date: 2025-08-26 00:49:52

1-(4-Trifluoromethylphenyl)piperazine Structure
1-(4-Trifluoromethylphenyl)piperazine structure
Common Name 1-(4-Trifluoromethylphenyl)piperazine
CAS Number 30459-17-7 Molecular Weight 230.230
Density 1.2±0.1 g/cm3 Boiling Point 309.1±42.0 °C at 760 mmHg
Molecular Formula C11H13F3N2 Melting Point 88-92 °C
MSDS Chinese USA Flash Point 140.7±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1-[4-(trifluoromethyl)phenyl]piperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 309.1±42.0 °C at 760 mmHg
Melting Point 88-92 °C
Molecular Formula C11H13F3N2
Molecular Weight 230.230
Flash Point 140.7±27.9 °C
Exact Mass 230.103088
PSA 15.27000
LogP 2.36
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.485

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;C: Corrosive;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933599090

 Synthetic Route

~97%

1-(4-Trifluoromethylphenyl)piperazine Structure

1-(4-Trifluorom...

CAS#:30459-17-7

Literature: LANXESS Deutschland GmbH Patent: US2005/250791 A1, 2005 ; Location in patent: Page/Page column 4 ;

~94%

1-(4-Trifluoromethylphenyl)piperazine Structure

1-(4-Trifluorom...

CAS#:30459-17-7

Literature: LANXESS Deutschland GmbH Patent: US2005/250791 A1, 2005 ; Location in patent: Page/Page column 4 ;

~%

1-(4-Trifluoromethylphenyl)piperazine Structure

1-(4-Trifluorom...

CAS#:30459-17-7

Literature: US2014/142114 A1, ; Page/Page column ;

~%

1-(4-Trifluoromethylphenyl)piperazine Structure

1-(4-Trifluorom...

CAS#:30459-17-7

Literature: WO2011/28947 A2, ; WO 2011/028947 A1

~33%

1-(4-Trifluoromethylphenyl)piperazine Structure

1-(4-Trifluorom...

CAS#:30459-17-7

Literature: Agarwal, Kamlesh C. Journal of the Indian Chemical Society, 1980 , vol. 57, # 11 p. 1170 - 1171

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-(4-Trifluoromethylphenyl)-piperazine
N-(alpha,alpha,alpha-Trifluoro-p-tolyl)piperazine
1-(α,α,α-Trifluoro-m-tolyl)piperazine
EINECS 250-210-3
4-(1-Piperazinyl)benzotrifluoride
1-(4-Trifluoromethylphenyl)piperazine
1-(3-Trifluoromethylphenyl)piperazine
Piperazine, 1-[4-(trifluoromethyl)phenyl]-
1-(4-Trifluoromethyl-phenyl)-piperazine
piperazine, 1-(4-trifluoromethylphenyl)-
1-[4-(Trifluoromethyl)phenyl]piperazine
1-(4-(Trifluoromethyl)phenyl)piperazine
1-(3-(trifluoromethyl)phenyl)piperazine
1-(α,α,α-Trifluoro-p-tolyl)piperazine
1-[3-(Trifluoromethyl)phenyl]piperazine
MFCD00040765
Piperazine, 1-[3-(trifluoromethyl)phenyl]-
[4-(trifluoromethyl)phenyl]piperazine
TFMPP
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