OAC1
Modify Date: 2024-01-02 20:11:07
OAC1 structure
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Common Name | OAC1 | ||
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| CAS Number | 300586-90-7 | Molecular Weight | 237.257 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 386.6±22.0 °C at 760 mmHg | |
| Molecular Formula | C14H11N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 187.6±22.3 °C | |
Use of OAC1OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process.IC50 value: Target: Oct4 activatorin vitro: OAC1 enhances the formation of Oct4-GFP+ colonies and accelerates the dynamics of reprogramming. OAC1 enhanced reprogramming efficiency through a mechanism that is independent of endogenous Oct4 promoter demethylation. OAC1 enhanced reprogramming efficiency through a mechanism that is distinct from suppressing p53-p21 expression. Luciferase assay revealed that OAC1 had no effect on Topflash activity, although BIO activated the Topflash reporter potently. OAC1 functions through a mechanism that is independent of the Wnt signaling. |
| Name | oac1 |
|---|---|
| Synonym | More Synonyms |
| Description | OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming process.IC50 value: Target: Oct4 activatorin vitro: OAC1 enhances the formation of Oct4-GFP+ colonies and accelerates the dynamics of reprogramming. OAC1 enhanced reprogramming efficiency through a mechanism that is independent of endogenous Oct4 promoter demethylation. OAC1 enhanced reprogramming efficiency through a mechanism that is distinct from suppressing p53-p21 expression. Luciferase assay revealed that OAC1 had no effect on Topflash activity, although BIO activated the Topflash reporter potently. OAC1 functions through a mechanism that is independent of the Wnt signaling. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 386.6±22.0 °C at 760 mmHg |
| Molecular Formula | C14H11N3O |
| Molecular Weight | 237.257 |
| Flash Point | 187.6±22.3 °C |
| Exact Mass | 237.090210 |
| PSA | 57.78000 |
| LogP | 1.19 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.755 |
| RIDADR | NONH for all modes of transport |
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| N-(1H-Pyrrolo[2,3-c]pyridin-5-yl)benzamide |
| Benzamide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- |