Teneliximab

Modify Date: 2025-08-26 11:18:25

Teneliximab Structure
Teneliximab structure
Common Name Teneliximab
CAS Number 299423-37-3 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Teneliximab


Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion[1].

 Names

Name Teneliximab

 Teneliximab Biological Activity

Description Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion[1].
Related Catalog
In Vitro Teneliximab (Chi220, BMS-224819) 的作用不仅仅是通过清除CD20承载细胞介导的,联合治疗没有显著损害已建立的抗病毒免疫[2]。
References

[1]. Maria A Argiriadi, et al. CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol. 2019 Aug 5;20(1):29.  

[2]. Andrew B Adams, et al. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. J Immunol. 2005 Jan 1;174(1):542-50.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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