Teneliximab

Names

[ Name ]:
Teneliximab

Biological Activity

[Description]:

Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

[In Vitro]

Teneliximab (Chi220, BMS-224819) 的作用不仅仅是通过清除CD20承载细胞介导的，联合治疗没有显著损害已建立的抗病毒免疫[2]。

[References]

[1]. Maria A Argiriadi, et al. CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol. 2019 Aug 5;20(1):29.

[2]. Andrew B Adams, et al. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. J Immunol. 2005 Jan 1;174(1):542-50.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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