HDAC-IN-59

Modify Date: 2025-09-04 07:00:24

HDAC-IN-59 Structure
HDAC-IN-59 structure
Common Name HDAC-IN-59
CAS Number 2944459-43-0 Molecular Weight 391.42
Density N/A Boiling Point N/A
Molecular Formula C20H25NO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HDAC-IN-59


HDAC-IN-59 (compound 13a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-59 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].

 Names

Name HDAC-IN-59

 HDAC-IN-59 Biological Activity

Description HDAC-IN-59 (compound 13a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-59 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].
Related Catalog
References

[1]. Yang Y, et, al. Design, Synthesis, and Biological Evaluation of Histone Deacetylase Inhibitors Derived from Erianin and Its Derivatives. ChemMedChem. 2023 Jul 3;18(13):e202300108.  

 Chemical & Physical Properties

Molecular Formula C20H25NO7
Molecular Weight 391.42
InChIKey XDHAEWQLLZOBOE-UHFFFAOYSA-N
SMILES COc1ccc(CCc2cc(OC)c(OC)c(OC)c2)cc1OCC(=O)NO
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