h-NTPDase-IN-3

Modify Date: 2025-09-18 13:30:53

h-NTPDase-IN-3 Structure
h-NTPDase-IN-3 structure
Common Name h-NTPDase-IN-3
CAS Number 2939933-10-3 Molecular Weight 290.34
Density N/A Boiling Point N/A
Molecular Formula C16H10N4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of h-NTPDase-IN-3


h-NTPDase-IN-3 (compound 4d) is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8).

 Names

Name h-NTPDase-IN-3

 h-NTPDase-IN-3 Biological Activity

Description h-NTPDase-IN-3 (compound 4d) is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8).
Related Catalog
Target

IC50: 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8)

References

[1]. Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.

 Chemical & Physical Properties

Molecular Formula C16H10N4S
Molecular Weight 290.34
InChIKey ZUSVATVCNQIYMR-UHFFFAOYSA-N
SMILES c1cncc(-c2csc3c(-c4cccnc4)ncnc23)c1
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