BI‑3231
Modify Date: 2025-09-11 22:29:49
BI‑3231 structure
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Common Name | BI‑3231 | ||
|---|---|---|---|---|
| CAS Number | 2894848-07-6 | Molecular Weight | 380.37 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H14F2N4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BI‑3231BI 3231 is a potent and selective hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases[1]. |
| Name | BI‑3231 |
|---|
| Description | BI 3231 is a potent and selective hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases[1]. |
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| Related Catalog | |
| Target |
hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13)[1] |
| In Vitro | BI 3231 在肝微粒体中表现出高代谢稳定性，在肝细胞中表现出中等代谢稳定性[1]。 |
| In Vivo | BI 3231 从血浆中迅速清除，但在 48 h 内仍保持相当大的肝脏暴露[1]。 |
| References |
| Molecular Formula | C16H14F2N4O3S |
|---|---|
| Molecular Weight | 380.37 |