OXi8007

Modify Date: 2025-08-27 11:34:31

Use of OXi8007

OXi8007 is a water-soluble phosphate prodrug of OXi8006, a tubulin-binding compound.

Name	Disodium 2-methoxy-5-[6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-2-yl]phenyl phosphate
Synonym	More Synonyms

Description	OXi8007 is a water-soluble phosphate prodrug of OXi8006, a tubulin-binding compound.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Strecker TE, et al. The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts. Cancer Lett. 2015 Dec 1;369(1):229-41.

Molecular Formula	C₂₆H₂₄NNa₂O₁₀P
Molecular Weight	587.423
Exact Mass	587.093323
InChIKey	GQIZTUAJGVBAFG-UHFFFAOYSA-L
SMILES	COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c(-c3ccc(OC)c(OP(=O)([O-])[O-])c3)[nH]c2c1.[Na+].[Na+]

Disodium 2-methoxy-5-[6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-2-yl]phenyl phosphate

Methanone, [6-methoxy-2-[4-methoxy-3-(phosphonooxy)phenyl]-1H-indol-3-yl](3,4,5-trimethoxyphenyl)-, sodium salt (1:2)

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