CMX990

Modify Date: 2025-08-26 16:51:35

CMX990 Structure
CMX990 structure
Common Name CMX990
CAS Number 2882934-64-5 Molecular Weight 491.50
Density N/A Boiling Point N/A
Molecular Formula C22H32F3N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CMX990


CMX990 is a SARS-CoV-2 3CL protease inhibitor. The EC90s for inhibiting SARS-CoV-2 were 9.6 nM and 101 nM in human bronchial epithelial cells (HBECs) and HeLa-ACE2 cells, respectively. CMX990 has good ADME and pharmacokinetic properties[1].

 Names

Name CMX990

 CMX990 Biological Activity

Description CMX990 is a SARS-CoV-2 3CL protease inhibitor. The EC90s for inhibiting SARS-CoV-2 were 9.6 nM and 101 nM in human bronchial epithelial cells (HBECs) and HeLa-ACE2 cells, respectively. CMX990 has good ADME and pharmacokinetic properties[1].
Related Catalog
Target

SARS-CoV-2[1]

References

[1]. Zhang FM et al. Discovery of highly potent covalent SARS-CoV-2 3CLpro inhibitors bearing 2-sulfoxyl-1,3,4-oxadiazole scaffold for combating COVID-19. Eur J Med Chem. 2023 Nov 15;260:115721.  

 Chemical & Physical Properties

Molecular Formula C22H32F3N3O6
Molecular Weight 491.50
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