2882934-64-5

2882934-64-5 structure

Name: CMX990
Chemical Name: CMX990
CAS Number: 2882934-64-5
Molecular Formula: C₂₂H₃₂F₃N₃O₆
Molecular Weight: 491.50
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2024-12-04 17:54:28
Modify Date: 2024-12-04 17:54:28
CMX990 is a SARS-CoV-2 3CL protease inhibitor. The EC90s for inhibiting SARS-CoV-2 were 9.6 nM and 101 nM in human bronchial epithelial cells (HBECs) and HeLa-ACE2 cells, respectively. CMX990 has good ADME and pharmacokinetic properties[1].

Name	CMX990

Description	CMX990 is a SARS-CoV-2 3CL protease inhibitor. The EC90s for inhibiting SARS-CoV-2 were 9.6 nM and 101 nM in human bronchial epithelial cells (HBECs) and HeLa-ACE2 cells, respectively. CMX990 has good ADME and pharmacokinetic properties[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	SARS-CoV-2[1]
References	[1]. Zhang FM et al. Discovery of highly potent covalent SARS-CoV-2 3CLpro inhibitors bearing 2-sulfoxyl-1,3,4-oxadiazole scaffold for combating COVID-19. Eur J Med Chem. 2023 Nov 15;260:115721.

Molecular Formula	C₂₂H₃₂F₃N₃O₆
Molecular Weight	491.50