4',6-Diamidino-2-phenylindole dihydrochloride

Modify Date: 2024-01-02 17:02:41

4',6-Diamidino-2-phenylindole dihydrochloride Structure
4',6-Diamidino-2-phenylindole dihydrochloride structure
Common Name 4',6-Diamidino-2-phenylindole dihydrochloride
CAS Number 28718-90-3 Molecular Weight 350.246
Density 1.41g/cm3 Boiling Point 545.4ºC at 760mmHg
Molecular Formula C16H17Cl2N5 Melting Point >300°C (dec.)
MSDS USA Flash Point 283.6ºC

 Use of 4',6-Diamidino-2-phenylindole dihydrochloride


DAPI dihydrochloride (4',6-diamidino-2-phenylindole) is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.

 Names

Name 2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide,dihydrochloride
Synonym More Synonyms

  Biological Activity

Description DAPI dihydrochloride (4',6-diamidino-2-phenylindole) is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.
Related Catalog
In Vitro DAPI (4',6-diamidino-2-phenylindole) is a DNA-specific probe which forms a fluorescent complex by attaching in the minor grove of A-T rich sequences of DNA. It also forms nonfluorescent intercalative complexes with double-stranded nucleic acids. DAPI can be used as a DNA-specific probe for flow cytometry, chromosome staining, DNA visualization and quantitation in histochemistry and biochemistry[1].
References

[1]. Kapuscinski J, et al. DAPI: a DNA-specific fluorescent probe. Biotech Histochem. 1995 Sep;70(5):220-33.

 Chemical & Physical Properties

Density 1.41g/cm3
Boiling Point 545.4ºC at 760mmHg
Melting Point >300°C (dec.)
Molecular Formula C16H17Cl2N5
Molecular Weight 350.246
Flash Point 283.6ºC
Exact Mass 349.086090
PSA 115.53000
LogP 5.60710
Vapour Pressure 5.96E-12mmHg at 25°C
Storage condition −20°C
Water Solubility H2O: 10 mg/mL heat or sonication may be required. Solutions stored in the dark at room temperature or 4 °C should be stable for 2 to 3 weeks.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25-S22
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NL5995050
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

2-(4-Amidinophenyl)indole-6-carboxamidine Dihydrochloride
EINECS 249-186-7
DAPI hydrochloride
2-(4-Carbamimidoylphenyl)-1H-indole-6-carboximidamide dihydrochloride
MFCD00012681
2-(4-Amidinophenyl)
1H-Indole-6-carboximidamide, 2-[4-(aminoiminomethyl)phenyl]-, hydrochloride (1:2)
4′,6′-Diamidino-2-phenylindole dihydrochloride
2-(4-Carbamimidoylphenyl)indole-6-carboximidamide Dihydrochloride
4',6-diamidine-2-phenylindole dihydrochloride
DAPI,Dihydrochloride
4,6-Diamidino-2-Phenylindole Dihydrochloride
DAPI dihydrochloride
4',6-Diamidino-2-phenylindole Dihydrochloride
2-(4-Amidinophenyl)-6-indolecarbamidine dihydrochloride
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Price: $66/10mM*1mLinDMSO

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