NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

Modify Date: 2025-10-20 13:13:45

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Structure
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT structure
Common Name NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
CAS Number 2857037-69-3 Molecular Weight 473.48
Density N/A Boiling Point N/A
Molecular Formula C26H23N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT


NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1].

 Names

Name NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

 NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Biological Activity

Description NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1].
Related Catalog
References

[1]. Andrew C. Phillips, et al. Anti-c-met antibody drug conjugates.WO2022232834.

 Chemical & Physical Properties

Molecular Formula C26H23N3O6
Molecular Weight 473.48
InChIKey JMAYYZUPPRJUBV-WNMGUVTHSA-N
SMILES CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc3c(cc1c2C12CC(N)(C1)C2)OCO3
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