Nasunin

Modify Date: 2025-08-25 08:36:32

Nasunin Structure
Nasunin structure
Common Name Nasunin
CAS Number 28463-30-1 Molecular Weight 955.26200
Density N/A Boiling Point N/A
Molecular Formula C42H47ClO23 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nasunin


Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity[1].

 Names

Name Nasumic

 Nasunin Biological Activity

Description Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity[1].
Related Catalog
In Vitro Nasunin at higher 10 µM suppresses microvessel outgrowth in an ex vivo angiogenesis assay using a rat aortic ring[1]. Nasunin suppresses HUVEC proliferation in a dose-dependent manner (50-200 µM)[1]. Nasunin diminishes LPS-induced nuclear factor-κB (NF-κB) activation by suppressing thedegradation of inhibitor of κB-α and nuclear translocation of p65 subunit of NF-κB. Nasunin also attenuates the phosphorylation of Akt and p38, signaling molecules involved in pro-inflammatory mediator production[1].
References

[1]. Kiminori Matsubara, et al. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels. J Agric Food Chem. 2005 Aug 10;53(16):6272-5.

[2]. Wataru Komatsu, et al. Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways. Biosci Biotechnol Biochem. 2017 Oct;81(10):1956-1966.

 Chemical & Physical Properties

Molecular Formula C42H47ClO23
Molecular Weight 955.26200
Exact Mass 954.22000
PSA 378.04000
InChIKey OUUYNFWYLXMNQZ-HNPHZNNWSA-N
SMILES CC1OC(OCC2OC(Oc3cc4c(OC5OC(CO)C(O)C(O)C5O)cc(O)cc4[o+]c3-c3cc(O)c(O)c(O)c3)C(O)C(O)C2O)C(O)C(O)C1OC(=O)C=Cc1ccc(O)cc1.[Cl-]
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