SF-1 antagonist-1

Modify Date: 2025-10-09 11:19:37

SF-1 antagonist-1 Structure
SF-1 antagonist-1 structure
Common Name SF-1 antagonist-1
CAS Number 2842079-86-9 Molecular Weight 490.41
Density N/A Boiling Point N/A
Molecular Formula C22H18F4N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SF-1 antagonist-1


SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of <200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer[1].

 Names

Name SF-1 antagonist-1

 SF-1 antagonist-1 Biological Activity

Description SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of <200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer[1].
Related Catalog
In Vitro SF-1 antagonist-1 (0-20 μM) affects SF-1 transcriptional activity with an EC50 value of <200 nM[1]. SF-1 antagonist-1 (0-20 μM; 48 h) affects proliferation of R2C cells[1]. Cell Proliferation Assay[1] Cell Line: Rat Leydig tumor cell line, R2C Concentration: 0-20 μM Incubation Time: 48 h Result: Inhibited proliferation of R2C cells with an EC50 value of <200 nM.
References

[1]. Raheja Neil, et al. PYRAZOLOPYRIMIDINONE COMPOUNDS. WO2022204481. 2022.

 Chemical & Physical Properties

Molecular Formula C22H18F4N6O3
Molecular Weight 490.41
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