CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
MC5525000
-
CHEMICAL NAME :
-
Glycolic acid, monosodium salt
-
CAS REGISTRY NUMBER :
-
2836-32-0
-
LAST UPDATED :
-
199701
-
DATA ITEMS CITED :
-
8
-
MOLECULAR FORMULA :
-
C2-H3-O3.Na
-
MOLECULAR WEIGHT :
-
98.04
-
WISWESSER LINE NOTATION :
-
Q1VO &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
7110 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,656,1986
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
6700 mg/kg
-
TOXIC EFFECTS :
-
Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes primarily in glomeruli Blood - changes in spleen
-
REFERENCE :
-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 29(12),53,1985
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Mammal - cat
-
DOSE/DURATION :
-
500 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - food intake (animal) Behavioral - muscle weakness Behavioral - ataxia
-
REFERENCE :
-
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 31,306,1942 ** OTHER MULTIPLE DOSE TOXICITY DATA **
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
78 gm/kg/78D-C
-
TOXIC EFFECTS :
-
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
-
REFERENCE :
-
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 6,227,1956 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3308 No. of Facilities: 454 (estimated) No. of Industries: 12 No. of Occupations: 31 No. of Employees: 10491 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3308 No. of Facilities: 896 (estimated) No. of Industries: 14 No. of Occupations: 17 No. of Employees: 21831 (estimated) No. of Female Employees: 6316 (estimated)
|
