TLR7 agonist 14

Modify Date: 2025-08-25 14:04:46

TLR7 agonist 14 Structure
TLR7 agonist 14 structure
 Common Name TLR7 agonist 14
CAS Number 2832199-45-6 Molecular Weight 516.63
Density N/A Boiling Point N/A
Molecular Formula C29H36N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TLR7 agonist 14


TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].

 Names

Name TLR7 agonist 14

 TLR7 agonist 14 Biological Activity

Description TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].
Related Catalog
Target

TLR7:18 nM (IC50)

References

[1]. Emma G DeYoung, et al. Synthesis and Optimization of 1-Substituted Imidazo[4,5- c]quinoline TLR7 Agonists. ACS Med Chem Lett. 2023 Sep 14;14(10):1358-1368.  

 Chemical & Physical Properties

Molecular Formula C29H36N6O3
Molecular Weight 516.63
InChIKey QLONMNKKVKTOHQ-UHFFFAOYSA-N
SMILES CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CCNC(=O)OC(C)(C)C)cc1
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Chemsrc provides TLR7 agonist 14(CAS#:2832199-45-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TLR7 agonist 14 are included as well.>> amp version: TLR7 agonist 14

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