Daurinoline

Modify Date: 2024-01-02 19:19:47

Daurinoline structure	Common Name	Daurinoline
	CAS Number	2831-75-6	Molecular Weight	610.739
	Density	1.2±0.1 g/cm3	Boiling Point	724.5±60.0 °C at 760 mmHg
	Molecular Formula	C₃₇H₄₂N₂O₆	Melting Point	100-103ºC
	MSDS	N/A	Flash Point	392.0±32.9 °C

Use of Daurinoline

Daurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research[1].

Name	(1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-i soquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl- 1,2,3,4-tetrahydro-6-isoquinolinol
Synonym	More Synonyms

Description	Daurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Daurinoline inhibits the proliferation, migration, invasion and EMT phenotype of chemo-resistant NSCLC cells[1].
References	[1]. Dan-Dan Li, et al. Daurinoline suppressed the migration and invasion of chemo-resistant human non-small cell lung cancer cells by reversing EMT and Notch-1 and sensitized the cells to Taxol. Environ Toxicol Pharmacol. 2019 Feb;66:109-115.

Density	1.2±0.1 g/cm3
Boiling Point	724.5±60.0 °C at 760 mmHg
Melting Point	100-103ºC
Molecular Formula	C₃₇H₄₂N₂O₆
Molecular Weight	610.739
Flash Point	392.0±32.9 °C
Exact Mass	610.304260
PSA	83.86000
LogP	5.84
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.618
Storage condition	2-8℃

13-Ethyleneacetaldaunomycinone

(1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol

(1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydro-6-isoquinolinol

5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-8-(2-methyl-1,3-dioxolan-2-yl)-,(8S-cis)-(9CI)

Daurinoline

Daunomycinone 13-ethylene ketal

6-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-[2-hydroxy-5-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenyl]methyl]-7-methoxy-2-methyl-, (1R)-