MRV03-037

Modify Date: 2024-04-03 11:31:59

MRV03-037 structure	Common Name	MRV03-037
	CAS Number	2797066-28-3	Molecular Weight	230.07
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₉BN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MRV03-037

MRV03-037 is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-037 prevents gut bacterial genotoxin production[1].

Name	MRV03-037

Description	MRV03-037 is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-037 prevents gut bacterial genotoxin production[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	MRV03-037 (compound 1; 0.01 nM-0.1 mM for 1 h) inhibits ClbP acitivity in E. coli BL21 overexpressing ClbP[1].
References	[1]. Volpe MR, et al. A small molecule inhibitor prevents gut bacterial genotoxin production. Nat Chem Biol. 2022 Oct 17.

Molecular Formula	C₉H₁₉BN₂O₄
Molecular Weight	230.07