Tubulin polymerization-IN-43

Modify Date: 2025-08-26 02:41:10

Tubulin polymerization-IN-43 structure	Common Name	Tubulin polymerization-IN-43
	CAS Number	2773345-90-5	Molecular Weight	351.30
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₃F₄N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tubulin polymerization-IN-43

Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis[1].

Name	Tubulin polymerization-IN-43

Description	Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-43 disrupts cellular microtubule networks by targeting the Colchicine (HY-16569) site, and promots cell cycle arrest of leukemia cells at G2/M phase and cell apoptosis, as well as inhibiting angiogenesis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Wu H, et, al. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Eur J Med Chem. 2023 Aug 5;256:115470.

Molecular Formula	C₁₇H₁₃F₄N₃O
Molecular Weight	351.30
InChIKey	YTTBMLZFUZWEBE-UHFFFAOYSA-N
SMILES	COc1ccc(N(C)c2nc(C(F)(F)F)nc3ccc(F)cc23)cc1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tubulin polymerization-IN-43
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.