FDW028

Modify Date: 2024-01-10 10:52:13

FDW028 Structure
FDW028 structure
 Common Name FDW028
CAS Number 2768426-49-7 Molecular Weight 388.47
Density N/A Boiling Point N/A
Molecular Formula C22H24N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FDW028


FDW028 a potent and highly selective FUT8 inhibitor. FUT8 exhibits potent anti-tumor activity by defucosylation and impelling lysosomal degradation of B7-H3 through the chaperone-mediated autophagy (CMA) pathway. FDW028 can be used for metastatic colorectal cancer (mCRC) research[1].

 Names

Name FDW028

 FDW028 Biological Activity

Description FDW028 a potent and highly selective FUT8 inhibitor. FUT8 exhibits potent anti-tumor activity by defucosylation and impelling lysosomal degradation of B7-H3 through the chaperone-mediated autophagy (CMA) pathway. FDW028 can be used for metastatic colorectal cancer (mCRC) research[1].
Related Catalog
References

[1]. Wang M, et al. FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer. Cell Death Dis. 2023 Aug 3;14(8):495.  

 Chemical & Physical Properties

Molecular Formula C22H24N6O
Molecular Weight 388.47
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Chemsrc provides FDW028(CAS#:2768426-49-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of FDW028 are included as well.>> amp version: FDW028

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