PHD2-IN-1

Modify Date: 2025-08-25 22:33:24

PHD2-IN-1 structure	Common Name	PHD2-IN-1
	CAS Number	2768219-28-7	Molecular Weight	446.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₃ClN₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PHD2-IN-1

PHD2-IN-1 is a potent and orally active inhibitor of HIF prolyl hydroxylase 2 (PHD2) with an IC50 of 22.53 nM. PHD2-IN-1 can be used for anemia research[1].

Name	PHD2-IN-1

Description	PHD2-IN-1 is a potent and orally active inhibitor of HIF prolyl hydroxylase 2 (PHD2) with an IC50 of 22.53 nM. PHD2-IN-1 can be used for anemia research[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase
References	[1]. Wu Y, et.al. Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia. J Med Chem. 2023 Jul 13;66(13):8545-8563.

Molecular Formula	C₂₁H₂₃ClN₄O₅
Molecular Weight	446.88
InChIKey	PNWJJULLNCIIMB-UHFFFAOYSA-N
SMILES	O=C(O)CNC(=O)c1ncc(C2CCN(C(=O)CNc3ccc(Cl)cc3)CC2)cc1O

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