SWTX-143

Modify Date: 2024-01-08 08:52:17

SWTX-143 structure	Common Name	SWTX-143
	CAS Number	2766575-48-6	Molecular Weight	361.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₈F₃N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SWTX-143

SWTX-143 is a novel covalent YAP/TAZ-TEAD inhibitor that binds to the palmitoylation pocket of all four TEAD isoforms. SWTX-143 causes irreversible and specific inhibition of the transcriptional activity of YAP/TAZ-TEAD and shows antitumor activity[1].

Name	SWTX-143

Description	SWTX-143 is a novel covalent YAP/TAZ-TEAD inhibitor that binds to the palmitoylation pocket of all four TEAD isoforms. SWTX-143 causes irreversible and specific inhibition of the transcriptional activity of YAP/TAZ-TEAD and shows antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> YAP
References	[1]. Hanne Hillen, et al. A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models. Mol Cancer Ther. 2023 Sep 23.

Molecular Formula	C₁₉H₁₈F₃N₃O
Molecular Weight	361.36

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SWTX-143
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: SWTX-143
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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SWTX-143

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.