CL4F8-6

Modify Date: 2024-01-13 13:30:07

CL4F8-6 Structure
CL4F8-6 structure
Common Name CL4F8-6
CAS Number 2766493-12-1 Molecular Weight 808.35
Density N/A Boiling Point N/A
Molecular Formula C51H101NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL4F8-6


CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice[1].

 Names

Name CL4F8-6

 CL4F8-6 Biological Activity

Description CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice[1].
Related Catalog
References

[1]. Kazuki Hashiba, et al. Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA. Small Science. 09 November 2022.

 Chemical & Physical Properties

Molecular Formula C51H101NO5
Molecular Weight 808.35
InChIKey FIQJUNNYZXWQKM-UHFFFAOYSA-N
SMILES CCCCCCC(CCCCCC)C(=O)OCCCCCCC(O)(CCCCCCOC(=O)C(CCCCCC)CCCCCC)CCCCN(CCC)CCC
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