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CL4F8-6

Names

[ CAS No. ]:
2766493-12-1

[ Name ]:
CL4F8-6

Biological Activity

[Description]:

CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Kazuki Hashiba, et al. Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA. Small Science. 09 November 2022.

Chemical & Physical Properties

[ Molecular Formula ]:
C51H101NO5

[ Molecular Weight ]:
808.35


Related Compounds

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