HL-8

Modify Date: 2025-08-24 22:46:24

HL-8 Structure
HL-8 structure
 Common Name HL-8
CAS Number 2766352-64-9 Molecular Weight 1144.27
Density N/A Boiling Point N/A
Molecular Formula C57H59F2N11O9S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HL-8


HL-8 is a PROTAC molecule targeting PI3K kinase. HL-8 has a significant and complete degradation effect on PI3K kinase at a concentration of 10 μM within 8 h. HL-8 has the potential for the research of cancer diseases[1].

 Names

Name HL-8

 HL-8 Biological Activity

Description HL-8 is a PROTAC molecule targeting PI3K kinase. HL-8 has a significant and complete degradation effect on PI3K kinase at a concentration of 10 μM within 8 h. HL-8 has the potential for the research of cancer diseases[1].
Related Catalog
References

[1]. Wang H, et al. Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase. Bioorg Med Chem. 2022 May 1;61:116707.

 Chemical & Physical Properties

Molecular Formula C57H59F2N11O9S2
Molecular Weight 1144.27
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Chemsrc provides HL-8(CAS#:2766352-64-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of HL-8 are included as well.>> amp version: HL-8

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