BTK-IN-26

Modify Date: 2024-01-30 16:18:11

BTK-IN-26 Structure
BTK-IN-26 structure
Common Name BTK-IN-26
CAS Number 2762043-61-6 Molecular Weight 507.57
Density N/A Boiling Point N/A
Molecular Formula C27H26D3FN6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BTK-IN-26


BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1].

 Names

Name BTK-IN-26

 BTK-IN-26 Biological Activity

Description BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1].
Related Catalog
References

[1]. Xiangyang Chen, et al. Heterocyclic compounds as btk inhibitors. Patent, WO2022037649A1.

 Chemical & Physical Properties

Molecular Formula C27H26D3FN6O3
Molecular Weight 507.57
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