BTK-IN-26

Names

[ CAS No. ]:
2762043-61-6

[ Name ]:
BTK-IN-26

Biological Activity

[Description]:

BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[References]

[1]. Xiangyang Chen, et al. Heterocyclic compounds as btk inhibitors. Patent, WO2022037649A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₆D₃FN₆O₃

[ Molecular Weight ]:
507.57

Related Compounds

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