BT424

Modify Date: 2025-08-25 17:06:50

BT424 structure	Common Name	BT424
	CAS Number	2755180-37-9	Molecular Weight	421.08
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₅BCl₂N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BT424

BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model[1].

Name	BT424

Description	BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src Research Areas >> Inflammation/Immunology
References	[1]. Chen M, et al. HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Nat Commun. 2023 Jul 18;14(1):4297.

Molecular Formula	C₂₂H₁₅BCl₂N₂O₂
Molecular Weight	421.08
InChIKey	SYIZHZBXDOQNIR-UHFFFAOYSA-N
SMILES	Clc1cc(Cl)c2c(c1)C=C(C1=NB(c3ccccc3)ON1)C(c1ccccc1)O2

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