BT424

Names

[ CAS No. ]:
2755180-37-9

[ Name ]:
BT424

Biological Activity

[Description]:

BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model[1].

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src
Research Areas >> Inflammation/Immunology

[References]

[1]. Chen M, et al. HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Nat Commun. 2023 Jul 18;14(1):4297.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H15BCl2N2O2

[ Molecular Weight ]:
421.08

Related Compounds

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