Epinodosinol

Modify Date: 2025-11-07 23:06:00

Use of Epinodosinol

Epinodosinol is a diterpenoid derived from plant Rabdosia angustifolia. Epinodosinol has inhibitory activity against certain cancer cells[1].

Name	Epinodosinol
Synonym	More Synonyms

Description	Epinodosinol is a diterpenoid derived from plant Rabdosia angustifolia. Epinodosinol has inhibitory activity against certain cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Epinodosinol (0-100 μM; 48 h) exhibits inhibitory activities against HepG2, GLC-82 and HL-60 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: HepG2, GLC-82 and HL-60 cells Concentration: 0-100 μM Incubation Time: 48 h Result: Exhibited inhibitory activities against HepG2, GLC-82 and HL-60 cells with IC50s of 77.19 ± 0.33 μM, 59.44 ± 6.67 μM and 38.61 ± 2.77 μM, respectively.
References	[1]. Ding L, Liu B, et al. Comparison of cytotoxicity and DNA damage potential induced by ent-kaurene diterpenoids from Isodon plant. Nat Prod Res. 2011 Sep;25(15):1402-11.

Molecular Formula	C₂₀H₂₈O₆
Molecular Weight	364.43300
Exact Mass	364.18900
PSA	96.22000
LogP	0.98720
Vapour Pressure	2.28E-17mmHg at 25°C
InChIKey	GVECAQZXEMZIGZ-OXUJBKPGSA-N
SMILES	C=C1C2CC(O)C3C(C2)(C(=O)OC2CCC(C)(C)C4C(O)OCC243)C1O

Enmein,1-deoxo-13-deoxy-1,5-dihydroxy-,(1a,5a)

(3as,6r,8r,10s,10as,10bs,13r,13ar)-6,10,13-trihydroxy-1,1-dimethyl-7-methylidenedodecahydro-5a,8-methanocyclohepta[c]furo[3,4-e]chromen-5-one

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