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27548-88-5

27548-88-5 structure
27548-88-5 structure
  • Name: Epinodosinol
  • Chemical Name: Epinodosinol
  • CAS Number: 27548-88-5
  • Molecular Formula: C20H28O6
  • Molecular Weight: 364.43300
  • Catalog: Research Areas Cancer
  • Create Date: 2016-09-02 14:42:36
  • Modify Date: 2024-10-05 13:27:54
  • Epinodosinol is a diterpenoid derived from plant Rabdosia angustifolia. Epinodosinol has inhibitory activity against certain cancer cells[1].

Name Epinodosinol
Synonyms Enmein,1-deoxo-13-deoxy-1,5-dihydroxy-,(1a,5a)
(3as,6r,8r,10s,10as,10bs,13r,13ar)-6,10,13-trihydroxy-1,1-dimethyl-7-methylidenedodecahydro-5a,8-methanocyclohepta[c]furo[3,4-e]chromen-5-one
Description Epinodosinol is a diterpenoid derived from plant Rabdosia angustifolia. Epinodosinol has inhibitory activity against certain cancer cells[1].
Related Catalog
In Vitro Epinodosinol (0-100 μM; 48 h) exhibits inhibitory activities against HepG2, GLC-82 and HL-60 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: HepG2, GLC-82 and HL-60 cells Concentration: 0-100 μM Incubation Time: 48 h Result: Exhibited inhibitory activities against HepG2, GLC-82 and HL-60 cells with IC50s of 77.19 ± 0.33 μM, 59.44 ± 6.67 μM and 38.61 ± 2.77 μM, respectively.
References

[1]. Ding L, Liu B, et al. Comparison of cytotoxicity and DNA damage potential induced by ent-kaurene diterpenoids from Isodon plant. Nat Prod Res. 2011 Sep;25(15):1402-11.  

Molecular Formula C20H28O6
Molecular Weight 364.43300
Exact Mass 364.18900
PSA 96.22000
LogP 0.98720
Vapour Pressure 2.28E-17mmHg at 25°C
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