27548-88-5

27548-88-5 structure

Name: Epinodosinol
Chemical Name: Epinodosinol
CAS Number: 27548-88-5
Molecular Formula: C₂₀H₂₈O₆
Molecular Weight: 364.43300
Catalog: Research Areas Cancer
Create Date: 2016-09-02 14:42:36
Modify Date: 2025-11-07 23:06:00
Epinodosinol is a diterpenoid derived from plant Rabdosia angustifolia. Epinodosinol has inhibitory activity against certain cancer cells[1].

Name	Epinodosinol
Synonyms	Enmein,1-deoxo-13-deoxy-1,5-dihydroxy-,(1a,5a) (3as,6r,8r,10s,10as,10bs,13r,13ar)-6,10,13-trihydroxy-1,1-dimethyl-7-methylidenedodecahydro-5a,8-methanocyclohepta[c]furo[3,4-e]chromen-5-one

Description	Epinodosinol is a diterpenoid derived from plant Rabdosia angustifolia. Epinodosinol has inhibitory activity against certain cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Epinodosinol (0-100 μM; 48 h) exhibits inhibitory activities against HepG2, GLC-82 and HL-60 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: HepG2, GLC-82 and HL-60 cells Concentration: 0-100 μM Incubation Time: 48 h Result: Exhibited inhibitory activities against HepG2, GLC-82 and HL-60 cells with IC50s of 77.19 ± 0.33 μM, 59.44 ± 6.67 μM and 38.61 ± 2.77 μM, respectively.
References	[1]. Ding L, Liu B, et al. Comparison of cytotoxicity and DNA damage potential induced by ent-kaurene diterpenoids from Isodon plant. Nat Prod Res. 2011 Sep;25(15):1402-11.