RXFP3/4 agonist 2

Modify Date: 2025-08-26 16:16:46

RXFP3/4 agonist 2 Structure
RXFP3/4 agonist 2 structure
Common Name RXFP3/4 agonist 2
CAS Number 2752378-78-0 Molecular Weight 402.45
Density N/A Boiling Point N/A
Molecular Formula C22H22N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RXFP3/4 agonist 2


RXFP3/4 agonist 2 is a potent, nonpeptide dual RXFP3/4 agonist (EC50=3.1 and 2.7 nM). RXFP3/4 agonist 2 also potently promotes interactions between RXFP3 and β-arrestin-2 with EC50 values in the range of 10-22 nM[1].

 Names

Name RXFP3/4 agonist 2

 RXFP3/4 agonist 2 Biological Activity

Description RXFP3/4 agonist 2 is a potent, nonpeptide dual RXFP3/4 agonist (EC50=3.1 and 2.7 nM). RXFP3/4 agonist 2 also potently promotes interactions between RXFP3 and β-arrestin-2 with EC50 values in the range of 10-22 nM[1].
Related Catalog
References

[1]. Guan D, et al. Indole-Containing Amidinohydrazones as Nonpeptide, Dual RXFP3/4 Agonists: Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies. J Med Chem. 2021;64(24):17866-17886.

 Chemical & Physical Properties

Molecular Formula C22H22N6O2
Molecular Weight 402.45
InChIKey XIVYUSRYHWXGLX-UVHMKAGCSA-N
SMILES COC(=O)c1ccc(CCN=C(N)NN=Cc2c[nH]c3c(C)cc(C#N)cc23)cc1
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