CCG-271423

Modify Date: 2025-08-26 23:30:38

CCG-271423 Structure
CCG-271423 structure
 Common Name CCG-271423
CAS Number 2750413-88-6 Molecular Weight 466.53
Density N/A Boiling Point N/A
Molecular Formula C28H26N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CCG-271423


CCG-271423 is a potent and selective GRK5 inhibitor with IC50 values of 0.0021 μM and 44 μM for GRK5 and GRK2, respectively. CCG-271423 inhibits cardiomyocyte contractility and decreases in Ca2+ transience[1].

 Names

Name CCG-271423

 CCG-271423 Biological Activity

Description CCG-271423 is a potent and selective GRK5 inhibitor with IC50 values of 0.0021 μM and 44 μM for GRK5 and GRK2, respectively. CCG-271423 inhibits cardiomyocyte contractility and decreases in Ca2+ transience[1].
Related Catalog
Target

IC50: 0.0021 μM (GRK5) and 44 μM (GRK5)[1]

In Vitro CCG-271423 (1 μM) does not alter cardiomyocyte contractility and decreases in Ca2+ transience[1].
References

[1]. Rowlands R, et, al. Expanding the Arsenal: Development of G-Protein Receptor Kinase 5 Inhibitors Utilizing a Covalent Strategy.

 Chemical & Physical Properties

Molecular Formula C28H26N4O3
Molecular Weight 466.53
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Chemsrc provides CCG-271423(CAS#:2750413-88-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of CCG-271423 are included as well.>> amp version: CCG-271423

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