CCG-271423

Modify Date: 2024-04-07 11:49:46

CCG-271423 structure	Common Name	CCG-271423
	CAS Number	2750413-88-6	Molecular Weight	466.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₆N₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CCG-271423

CCG-271423 is a potent and selective GRK5 inhibitor with IC50 values of 0.0021 μM and 44 μM for GRK5 and GRK2, respectively. CCG-271423 inhibits cardiomyocyte contractility and decreases in Ca2+ transience[1].

Name	CCG-271423

Description	CCG-271423 is a potent and selective GRK5 inhibitor with IC50 values of 0.0021 μM and 44 μM for GRK5 and GRK2, respectively. CCG-271423 inhibits cardiomyocyte contractility and decreases in Ca2+ transience[1].
Related Catalog	Research Areas >> Cardiovascular Disease
Target	IC50: 0.0021 μM (GRK5) and 44 μM (GRK5)[1]
In Vitro	CCG-271423 (1 μM) does not alter cardiomyocyte contractility and decreases in Ca2+ transience[1].
References	[1]. Rowlands R, et, al. Expanding the Arsenal: Development of G-Protein Receptor Kinase 5 Inhibitors Utilizing a Covalent Strategy.

Molecular Formula	C₂₈H₂₆N₄O₃
Molecular Weight	466.53