Xanthohumol D

Modify Date: 2024-01-13 01:29:07

Xanthohumol D Structure
Xanthohumol D structure
Common Name Xanthohumol D
CAS Number 274675-25-1 Molecular Weight 370.396
Density 1.3±0.1 g/cm3 Boiling Point 624.2±55.0 °C at 760 mmHg
Molecular Formula C21H22O6 Melting Point N/A
MSDS N/A Flash Point 220.9±25.0 °C

 Use of Xanthohumol D


Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro[1][2].

 Names

Name Xanthohumol D
Synonym More Synonyms

 Xanthohumol D Biological Activity

Description Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro[1][2].
Related Catalog
Target

IC50: 110 μM (Quinone reductase-2)[1]

References

[1]. Choi Y, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Anal Chem. 2011 Feb 1;83(3):1048-52.

[2]. Tronina T, et al. Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro. Bioorg Med Chem. 2013 Apr 1;21(7):2001-6.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 624.2±55.0 °C at 760 mmHg
Molecular Formula C21H22O6
Molecular Weight 370.396
Flash Point 220.9±25.0 °C
Exact Mass 370.141632
PSA 107.22000
LogP 3.54
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.652

 Safety Information

Hazard Codes Xi

 Synonyms

(2E)-1-[2,4-Dihydroxy-3-(2-hydroxy-3-methylbut-3-en-1-yl)-6-methoxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
(2E)-1-[2,4-Dihydroxy-3-(2-hydroxy-3-methyl-3-buten-1-yl)-6-methoxyphenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-[2,4-dihydroxy-3-(2-hydroxy-3-methyl-3-buten-1-yl)-6-methoxyphenyl]-3-(4-hydroxyphenyl)-, (2E)-
2-propen-1-one, 1-[2,4-dihydroxy-3-(2-hydroxy-3-methyl-3-butenyl)-6-methoxyphenyl]-3-(4-hydroxyphenyl)-, (2E)-
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Xanthohumol D
  • Price: ¥3900.0/5mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng




Get all suppliers and price by the below link:

Xanthohumol D suppliers

Xanthohumol D price