ALK-IN-27

Modify Date: 2024-01-08 19:14:42

ALK-IN-27 structure	Common Name	ALK-IN-27
	CAS Number	2739866-40-9	Molecular Weight	452.91
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₂ClFN₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ALK-IN-27

ALK-IN-27 (compound 1) is a potent ALK inhibitor. ALK-IN-27 shows antitumor activity. ALK-IN-27 has an IC50 of 2.7 nM for Ba/F3 CLIP1-LTK cell[1].

Name	ALK-IN-27

Description	ALK-IN-27 (compound 1) is a potent ALK inhibitor. ALK-IN-27 shows antitumor activity. ALK-IN-27 has an IC50 of 2.7 nM for Ba/F3 CLIP1-LTK cell[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
References	[1]. Jennifer Anne Green, et al. Methods of treating solid tumor using (19r)-5-chloro-3-ethyl-16-fluoro-10,19-dimethyl-20-oxa-3,4,10,11,23-pentaazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(24),2(6),4,8,11,13,15,17,21(25),22-decaen-22-amine. WO2023196910A1.

Molecular Formula	C₂₃H₂₂ClFN₆O
Molecular Weight	452.91
InChIKey	FWZSCAQEBTVTOM-GFCCVEGCSA-N
SMILES	CCn1nc(Cl)c2c1-c1cnc(N)c(c1)OC(C)c1cc(F)ccc1-c1nn(C)cc1C2

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