ALK-IN-27

Names

[ CAS No. ]:
2739866-40-9

[ Name ]:
ALK-IN-27

Biological Activity

[Description]:

ALK-IN-27 (compound 1) is a potent ALK inhibitor. ALK-IN-27 shows antitumor activity. ALK-IN-27 has an IC50 of 2.7 nM for Ba/F3 CLIP1-LTK cell[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK

[References]

[1]. Jennifer Anne Green, et al. Methods of treating solid tumor using (19r)-5-chloro-3-ethyl-16-fluoro-10,19-dimethyl-20-oxa-3,4,10,11,23-pentaazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(24),2(6),4,8,11,13,15,17,21(25),22-decaen-22-amine. WO2023196910A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H22ClFN6O

[ Molecular Weight ]:
452.91

Related Compounds

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