N-Desethyl Metoclopramide

Modify Date: 2024-01-06 14:15:21

N-Desethyl Metoclopramide structure	Common Name	N-Desethyl Metoclopramide
	CAS Number	27260-19-1	Molecular Weight	271.74300
	Density	1.2g/cm3	Boiling Point	414.5ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₈ClN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	204.5ºC

Name	4-Amino-5-chloro-N-[2-(ethylamino)ethyl]-2-methoxybenzamide
Synonym	More Synonyms

Density	1.2g/cm3
Boiling Point	414.5ºC at 760 mmHg
Molecular Formula	C₁₂H₁₈ClN₃O₂
Molecular Weight	271.74300
Flash Point	204.5ºC
Exact Mass	271.10900
PSA	79.87000
LogP	2.81700
Vapour Pressure	4.41E-07mmHg at 25°C
Index of Refraction	1.559

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ3330000

CHEMICAL NAME :: o-Anisamide, 4-amino-5-chloro-N-(2-(ethylamino)ethyl)-

CAS REGISTRY NUMBER :: 27260-19-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H18-Cl-N3-O2

MOLECULAR WEIGHT :: 271.78

WISWESSER LINE NOTATION :: 2M2MVR DZ CG FO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 242 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 245 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 41 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

N-Ethylethylene...

CAS#:110-72-5

4-Amino-5-Chlor...

CAS#:7206-70-4

~62%

N-Desethyl Meto...

CAS#:27260-19-1

Literature: NEKTAR THERAPEUTICS; CHENG, Lin; RIGGS-SAUTHIER, Jennifer; ANAND, Neel, K. Patent: WO2014/43707 A1, 2014 ; Location in patent: Paragraph 0166; 0167 ;