Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-Desethyl Metoclopramide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

27260-19-1

27260-19-1 structure

Name: N-Desethyl Metoclopramide
Chemical Name: 4-Amino-5-chloro-N-[2-(ethylamino)ethyl]-2-methoxybenzamide
CAS Number: 27260-19-1
Molecular Formula: C₁₂H₁₈ClN₃O₂
Molecular Weight: 271.74300
Create Date: 2016-01-31 09:22:22
Modify Date: 2024-01-06 14:15:21

Name	4-Amino-5-chloro-N-[2-(ethylamino)ethyl]-2-methoxybenzamide
Synonyms	ethylethylenediamine-4-amino-5-chloro-2-methoxybenzoic acid amide N-deethyl-Metoclopramide

Density	1.2g/cm3
Boiling Point	414.5ºC at 760 mmHg
Molecular Formula	C₁₂H₁₈ClN₃O₂
Molecular Weight	271.74300
Flash Point	204.5ºC
Exact Mass	271.10900
PSA	79.87000
LogP	2.81700
Vapour Pressure	4.41E-07mmHg at 25°C
Index of Refraction	1.559

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ3330000

CHEMICAL NAME :: o-Anisamide, 4-amino-5-chloro-N-(2-(ethylamino)ethyl)-

CAS REGISTRY NUMBER :: 27260-19-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H18-Cl-N3-O2

MOLECULAR WEIGHT :: 271.78

WISWESSER LINE NOTATION :: 2M2MVR DZ CG FO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 242 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 245 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 41 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,649,1976

110-72-5

7206-70-4

~62%

27260-19-1

Literature: NEKTAR THERAPEUTICS; CHENG, Lin; RIGGS-SAUTHIER, Jennifer; ANAND, Neel, K. Patent: WO2014/43707 A1, 2014 ; Location in patent: Paragraph 0166; 0167 ;

364-62-5

27260-19-1

Literature: Monkovic, Ivo; Wong, Henry; Bachand, Carol Synthesis, 1985 , # 8 p. 770 - 773

171367-22-9

27260-19-1

Literature: Monkovic, Ivo; Wong, Henry; Bachand, Carol Synthesis, 1985 , # 8 p. 770 - 773

Precursor 4
110-72-5 7206-70-4 364-62-5 171367-22-9
DownStream 0

27260-19-1	1346602-46-7
79049-30-2	94576-88-2
1184985-26-9	105310-07-4
1246819-11-3	37672-04-1
404034-55-5	1216894-33-5
1798040-26-2	1797367-89-5
1797560-05-4	1797875-25-2
1797905-52-2	1797643-86-7
1797560-64-5	1798422-22-6
1797560-73-6	1420816-58-5