Anti-inflammatory agent 22

Modify Date: 2024-01-07 17:31:00

Anti-inflammatory agent 22 Structure
Anti-inflammatory agent 22 structure
Common Name Anti-inflammatory agent 22
CAS Number 2721484-76-8 Molecular Weight 376.36
Density N/A Boiling Point N/A
Molecular Formula C22H16O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-inflammatory agent 22


Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC50 value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice[1].

 Names

Name Anti-inflammatory agent 22

 Anti-inflammatory agent 22 Biological Activity

Description Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC50 value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice[1].
Related Catalog
Target

TNF-α:14.6 μM (IC50)

References

[1]. Roh K, et al. Synthesis and evaluation of butein derivatives for in vitro and in vivo inflammatory response suppression in lymphedema. Eur J Med Chem. 2020;197:112280.

 Chemical & Physical Properties

Molecular Formula C22H16O6
Molecular Weight 376.36