2721484-76-8

2721484-76-8 structure

Name: Anti-inflammatory agent 22
Chemical Name: Anti-inflammatory agent 22
CAS Number: 2721484-76-8
Molecular Formula: C₂₂H₁₆O₆
Molecular Weight: 376.36
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-07-01 20:17:25
Modify Date: 2024-01-07 17:31:00
Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC50 value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice[1].

Name	Anti-inflammatory agent 22

Description	Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC50 value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice[1].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	TNF-α:14.6 μM (IC50)
References	[1]. Roh K, et al. Synthesis and evaluation of butein derivatives for in vitro and in vivo inflammatory response suppression in lymphedema. Eur J Med Chem. 2020;197:112280.

Molecular Formula	C₂₂H₁₆O₆
Molecular Weight	376.36