YAP-TEAD-IN-3
Modify Date: 2024-01-31 19:26:28
YAP-TEAD-IN-3 structure
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Common Name | YAP-TEAD-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2714434-21-4 | Molecular Weight | 529.96 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H26ClF2N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of YAP-TEAD-IN-3YAP-TEAD-IN-3 (compound 155) is a YAP/TAZ-TEAD inhibitor. YAP-TEAD-IN-3 inhibits Avi-humanTEAD4217-434 with an IC50 value of 9 nM. YAP-TEAD-IN-3 also inhibits NCI-H2052 with an GI50 of 0.048 μM (cell proliferation)，and an IC50 of 0.048 μM (YAP reporter gene expression)，respsectively[1]. |
| Name | YAP-TEAD-IN-3 |
|---|
| Description | YAP-TEAD-IN-3 (compound 155) is a YAP/TAZ-TEAD inhibitor. YAP-TEAD-IN-3 inhibits Avi-humanTEAD4217-434 with an IC50 value of 9 nM. YAP-TEAD-IN-3 also inhibits NCI-H2052 with an GI50 of 0.048 μM (cell proliferation)，and an IC50 of 0.048 μM (YAP reporter gene expression)，respsectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 9 nM (YAP-TEAD)[1] |
| References |
| Molecular Formula | C27H26ClF2N3O4 |
|---|---|
| Molecular Weight | 529.96 |
| InChIKey | HUVOYQMXUNTUAI-DCFHFQCYSA-N |
| SMILES | CNC(=O)c1cnc(OCCO)c(F)c1-c1c(Cl)c(F)cc2c1CC(c1ccccc1)(C1CCCN1)O2 |