3-(Tritylthio)propionic acid structure
|
Common Name | 3-(Tritylthio)propionic acid | ||
|---|---|---|---|---|
| CAS Number | 27144-18-9 | Molecular Weight | 348.458 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 503.8±38.0 °C at 760 mmHg | |
| Molecular Formula | C22H20O2S | Melting Point | 211-213°C | |
| MSDS | Chinese USA | Flash Point | 258.5±26.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 3-tritylsulfanylpropanoic acid |
|---|---|
| Synonym | More Synonyms |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 503.8±38.0 °C at 760 mmHg |
| Melting Point | 211-213°C |
| Molecular Formula | C22H20O2S |
| Molecular Weight | 348.458 |
| Flash Point | 258.5±26.8 °C |
| Exact Mass | 348.118408 |
| PSA | 62.60000 |
| LogP | 5.64 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.626 |
| InChIKey | AECGEIVNZGQBJT-UHFFFAOYSA-N |
| SMILES | O=C(O)CCSC(c1ccccc1)(c1ccccc1)c1ccccc1 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335-H413 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2930909090 |
|
~95%
3-(Tritylthio)p... CAS#:27144-18-9 |
| Literature: Contino-Pepin, Christiane; Parat, Audrey; Patinote, Cindy; Roscoe, Wendi A.; Karlik, Stephen J.; Pucci, Bernard ChemMedChem, 2010 , vol. 5, # 12 p. 2057 - 2064 |
|
~88%
3-(Tritylthio)p... CAS#:27144-18-9 |
| Literature: Mazzier; Mba; Zerbetto; Moretto Chemical Communications, 2014 , vol. 50, # 35 p. 4571 - 4574 |
|
~82%
3-(Tritylthio)p... CAS#:27144-18-9 |
| Literature: Gazal, Sharon; Gelerman, Garry; Ziv, Ofer; Karpov, Olga; Litman, Pninit; Bracha, Moshe; Afargan, Michel; Gilon, Chaim Journal of Medicinal Chemistry, 2002 , vol. 45, # 8 p. 1665 - 1671 |
| Precursor 5 | |
|---|---|
| DownStream 5 | |
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|
Cancer cell surface induced peptide folding allows intracellular translocation of drug.
J. Control. Release 209 , 317-26, (2015) Many lead molecules identified in drug discovery campaigns are eliminated from consideration due to poor solubility and low cell permeability. These orphaned molecules could have clinical value if sol... |
| 3-(Tritylsulfanyl)propanoic acid |
| 3-[(triphenylmethyl)thio]propionic acid |
| (Trt)-S-(CH2)2-COOH |
| S-Trityl-3-Mercaptopropionic Acid |
| 3-(tritylthio)propanoic acid |
| 3-(Tritylthio)propionic acid |
| MFCD00237291 |
| mpa(trt)-oh |
| Trt-SCH2CH2CO2H |
| Propanoic acid, 3-[(triphenylmethyl)thio]- |
| 3-Tritylmercapto-Propionicacid |
| Trt-S-CH2-CH2-COOH |
| Mpa(Trt) |