JAK kinase-IN-1

Modify Date: 2025-09-17 23:06:08

JAK kinase-IN-1 structure	Common Name	JAK kinase-IN-1
	CAS Number	2698389-43-2	Molecular Weight	407.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₉F₂N₇OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JAK kinase-IN-1

JAK kinase-IN-1 (Example 1) is a JAK inhibitor. JAK kinase-IN-1 inhibits TYK2, JAK1, JAK2 and JAK3 with IC50 values of 4.2 nM, 32 nM, 27 nM, 3473 nM respectively[1].

Name	JAK kinase-IN-1

Description	JAK kinase-IN-1 (Example 1) is a JAK inhibitor. JAK kinase-IN-1 inhibits TYK2, JAK1, JAK2 and JAK3 with IC50 values of 4.2 nM, 32 nM, 27 nM, 3473 nM respectively[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
References	[1]. Yao, Yuanshan, et al. Preparation of (pyrimidinyl)thiadiazabicyclo[3.2.1]octane derivatives as JAK kinase inhibitor and used for preventing and/or treating diseases or disorders related to JAK kinase activity or expression. Patent. WO2021180143.

Molecular Formula	C₁₇H₁₉F₂N₇OS
Molecular Weight	407.44

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