BBDDL2059

Modify Date: 2024-01-14 09:10:03

BBDDL2059 structure	Common Name	BBDDL2059
	CAS Number	2691174-27-1	Molecular Weight	512.66
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₆N₄O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BBDDL2059

BBDDL2059 is a selective covalent inhibitor of histone methyltransferase EZH2 with an IC50 of 1.5 nM for EZH2-Y641F. BBDDL2059 inhibits lymphoma cell growth at nanomolar concentrations and can be used for anticancer research[1].

Name	BBDDL2059

Description	BBDDL2059 is a selective covalent inhibitor of histone methyltransferase EZH2 with an IC50 of 1.5 nM for EZH2-Y641F. BBDDL2059 inhibits lymphoma cell growth at nanomolar concentrations and can be used for anticancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	EZH2 Y641F mutant type:1.5 nM (IC50)
References	[1]. Zhang Y, et.al. Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2. J Med Chem. 2023 Jun 8;66(11):7629-7644.

Molecular Formula	C₂₇H₃₆N₄O₄S
Molecular Weight	512.66

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BBDDL2059

Use of BBDDL2059

Names

BBDDL2059 Biological Activity

Chemical & Physical Properties