BBDDL2059

Modify Date: 2024-01-14 09:10:03

BBDDL2059 Structure
BBDDL2059 structure
 Common Name BBDDL2059
CAS Number 2691174-27-1 Molecular Weight 512.66
Density N/A Boiling Point N/A
Molecular Formula C27H36N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BBDDL2059


BBDDL2059 is a selective covalent inhibitor of histone methyltransferase EZH2 with an IC50 of 1.5 nM for EZH2-Y641F. BBDDL2059 inhibits lymphoma cell growth at nanomolar concentrations and can be used for anticancer research[1].

 Names

Name BBDDL2059

 BBDDL2059 Biological Activity

Description BBDDL2059 is a selective covalent inhibitor of histone methyltransferase EZH2 with an IC50 of 1.5 nM for EZH2-Y641F. BBDDL2059 inhibits lymphoma cell growth at nanomolar concentrations and can be used for anticancer research[1].
Related Catalog
Target

EZH2 Y641F mutant type:1.5 nM (IC50)

References

[1]. Zhang Y, et.al. Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2. J Med Chem. 2023 Jun 8;66(11):7629-7644.  

 Chemical & Physical Properties

Molecular Formula C27H36N4O4S
Molecular Weight 512.66
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Chemsrc provides BBDDL2059(CAS#:2691174-27-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of BBDDL2059 are included as well.>> amp version: BBDDL2059

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