AL-470

Modify Date: 2024-01-10 16:23:19

AL-470 Structure
AL-470 structure
Common Name AL-470
CAS Number 2671019-15-9 Molecular Weight 1328.20
Density N/A Boiling Point N/A
Molecular Formula C67H57N7O23 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AL-470


AL-470 is a potent antiviral agent with EC50 values of 0.27, 0.63, and 0.35 µM against HIV-1, HIV-2, and EV-A71, respectively[1].

 Names

Name AL-470

 AL-470 Biological Activity

Description AL-470 is a potent antiviral agent with EC50 values of 0.27, 0.63, and 0.35 µM against HIV-1, HIV-2, and EV-A71, respectively[1].
Related Catalog
Target

HIV-1:0.27 μM (EC50)

HIV-2:0.63 μM (EC50)

EV-A71:0.35 μM (EC50)

In Vitro AL-470 shows antiviral activity against the whole panel of mutant EV-A71 strains: EV-A71 BrCr wt (EC50 = 0.3 ± 0.03 µM), VP1_S184T (EC50 = 2.3 ± 0.6 µM), VP1_P246S (EC50 = 1.9 ± 0.04 µM), VP1_S184T_P246S (EC50 = 2.2 ± 0.08 µM)[1].
References

[1]. Olaia Martí-Marí, et al. Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors. Eur J Med Chem. 2022 Jul 5;237:114414.

 Chemical & Physical Properties

Molecular Formula C67H57N7O23
Molecular Weight 1328.20